Andrew John Butler, PhD, MBA

Andrew John Butler, PhD, MBA

Associate Professor, Rehabilitation Medicine

Office:   1441 Clifton RD NE
Suite RG07
Atlanta, GA 30322
Email:ajbutler@emory.edu (University)
Office:   (404) 712-5675 (Office)

Overview

Dr. Butler is a neuroscientist and physical therapist with a special interest in motor control, neuro-rehabilitation, functional neuroimaging, and transcranial magnetic stimulation. He is the co-director of TMS laboratory within the Center for Rehabilitation medicine. He is the Emory co-PI of the Functional Imaging in Constraint Induced Therapy (FICIT) study (R01 HD40984, George Wittenberg M.D.Ph.D, Wake Forest, PI) which evaluates the effect of constraint-induced movement therapy on cortical reorganization following stroke using TMS and fMRI co-registration among EXCITE participants.

Dr. Butler is currently the PI of a project investigating the use of mental imagery to improve motor deficits in patients with stroke National Center for Complementary and Alternative Medicine (NCCAM 5R21AT002138-02)

Education

2009 M.B.A. Finance Goizueta Atlanta, GA, USA
1998 M.S. Physical Therapy Physical Therapy Denton, TX, USA
1995 Ph.D. Motor Control Iowa City, IA, USA
1987 B.S. Biology, Chemistry Dubuque, IA, USA

Publications

Inman, C, James GA, Hamann S. Rajendra J. Pagnoni G. AJ Butler. (2011) Altered resting-state effective connectivity of fronto-parietal action guidance systems on the primary motor network following stroke. Neuroimage (in press).

Glielmi, CB, AJ Butler, DM Niyazov, WG Darling, CM Epstein, JL Alberts and XP Hu. (2011) Assessing low-frequency repetitive transcranial magnetic stimulation with functional magnetic resonance imaging: a case series. Physiotherapy Research International (in press). PMID:2176639

Qiu M, Darling WG, Morecraft RJ, Ni CC, Rajendra J, Butler AJ. (2011) White Matter Integrity Is a Stronger Predictor of Motor Function Than BOLD Response in Patients With Stroke. Neurorehabil Neural Repair. 25(3):275-284. PMID:21357529.

Kutner NG, Zhang R, Butler AJ, Wolf SL, Alberts JL. Quality-of-life change associated with robotic-assisted therapy to improve hand motor function in patients with subacute stroke: a randomized clinical trial. Phys Ther. 2010 Apr;90(4):493-504. PMID: 2018561

James, GA, Lu, Z-L, VanMeter, J. Sathian, K, Hu, X.P., Butler, A.J. (2009) Changes in resting-state effective connectivity in the motor network following rehabilitation of upper-extremity post-stroke paresis. Topics in Stroke Rehabilitation. 16(4): 270-281. PMID: 19740732

Zhang L, AJ Butler, CK Sun, V Sahgal, GF Wittenberg, and GH Yue. (2008) Fractal dimension assessment of brain white matter structural complexity post stroke in relation to upper-extremity motor function. Brain Research 1228:229-240. PMID: 18590710

Sawaki, L, AJ Butler, X Leng. PA Wassenaar, Y Mohammad, S Blanton, K Sathian, DS Nichols-Larsen, SL. Wolf, DC Good and GF Wittenberg. (2008) CIMT produces clinically relevant improvements and increased motor map area in patients 3-9 months post stroke. Neurorehabilitation and neural repair. 22:505-513. PMID: 18780885

M. Gregg, C. Hall and Butler, AJ. (2007) Measuring Movement Imagery Ability: Applications beyond Sport. Evidence-based Complementary and Alternative Medicine Dec. PMID: 18955294

Darling WG, Seitz RJ, Peltier S, Tellmann L, Butler AJ (2007) Visual cortex activation in kinesthetic guidance of reaching. Exp Brain Res 179: 607-619. PMID: 17171536

Butler AJ, Page SJ. (2006) Mental practice with motor imagery; evidence for motor recovery, and cortical reorganization after stroke. Archives of Physical Medicine and rehabilitation 87: (12 Suppl 2):S2-11. PMID: 17140874.

Butler AJ, Blanton, V. Rowe S, Wolf. (2006) Attempting to Improve Function and Quality of Life Using the FTM Protocol. Journal of Neurologic Physical Therapy. Vol 30(3):148-156.

Darling WG, Wolf SL, Butler AJ (2006) Variability of motor potentials evoked by transcranial magnetic stimulation depends on muscle activation. Exp Brain Res 174: 376-385. PMID: 16636787

Butler AJ, Kahn SE, Wolf SL, Weiss P. (2005): Finger extensor variability in TMS parameters among chronic stroke patients. J Neuroengineering Rehabil 2(1):10- PMID: 15927075

Niyazov DM, Butler AJ, Kadah YM, Epstein CM, Hu XP. (2005): Functional magnetic resonance imaging and transcranial magnetic stimulation: Effects of motor imagery, movement and coil orientation. Clin Neurophysiol 116(7):1601-10. PMID: 15953559.

Wolf S, Butler AJ, Alberts J and MW Kim. (2005) Contemporary linkages between EMG, kinetic, and stroke rehabilitation. Journal of electromyography and kinesiology. 15:229-230. PMID: 15763670.

Corneal S, Butler AJ, and SL Wolf. (2005). Intra- and intersubject reliability of abductor pollicis brevis muscle motor map characteristics with transcranial magnetic stimulation. Arch Phys Med Rehabil. Aug 2005;86(8):1670-1675. PMID: 16084825

Alberts J.L., Butler, AJ., S.L. Wolf. (2004) The effects of constraint-induced therapy on precision grip: a preliminary study. Neurorehabil Neural Repair, 2004. 18(4): p. 250-8. PMID: 15537995

Wolf SL, Butler AJ, Campana GI, Parris TA, Struys DM, Weinstein SR. (2004) Intra-subject reliability of parameters contributing to maps generated by transcranial magnetic stimulation in able-bodied adults. Clinical Neurophysiol 115:1740-1747. PMID: 15261852

Park, SW, Butler AJ., V. Cavalheiro, and S L. Wolf (2004). Changes in serial optical topography with constraint-induced movement therapy in stroke: a case study. Neurorehabil Neural Repair 18:95-105. PMID: 15228805

Butler, A.J., Fink, G., Dohle, C, Wunderlich, G., Tellman, L., Seitz, R. J., Zilles, K., and H.-J. Freund (2004) Neural mechanisms underlying reaching for remembered targets cued kinesthetically or visually in left or right hemispace, Human Brain Mapping 21(3):165-177. PMID: 14755836

Binkofski F, Butler AJ, Buccino G, Heide W, Fink G, Freund HJ, Seitz RJ (2003): Mirror apraxia affects the peripersonal mirror space. A combined lesion and cerebral activation study. Exp Brain Res 153:210-219.

Butler, AJ, Wolf, SL. Transcranial magnetic stimulation to assess cortical plasticity: A critical perspective for stroke rehabilitation (2003) J Rehabil Med; Suppl. 41:20-26. PMID: 12817653

Darling, W.G., Rizzo, M. and Butler, A J Disordered sensorimotor transformations for reaching following posterior cortical lesions, (2001). Neuropsychologia 39 (3):237-254. PMID: 11163603

Darling, W.G., Butler, A.J., Williams, T.E. Visual perception of head-fixed and trunk-fixed anterior/posterior axes (1996). Experimental Brain Research 112 (1):127-134. PMID: 8951415

Butler, A.J., Yue, G., and Darling, W.G. (1993) Variations in soleus H-reflexes as a function of plantarflexion torque in man. Brain Research, 632(1-2):95-104. PMID: 8149249

Awards and Honors

2010-2011 Woodruff Leadership Academy Fellow. Emory University School of Medicine and Robert W. Woodruff Health Sciences Center. Mentor: Michael M.E. Johns, M.D., and Stuart Zola, Ph.D.
02/2009 Invited participant. Physical Therapy and Society Summit (PASS). Leesburg, Virginia.
01/2007 Appointed as Fellow to the Council American Heart and Stroke Association
01/2007 Extramural Loan Repayment Program for Clinical Researchers (LRP-CR) National Institutes of Health
02/2003 Outstanding Research Proposal University of Virginia. NIH-NCMRR
04/2002 Young Investigator Award, International Stroke Symposium Center on Aging, University of Kansas Medical Center
06/2001 NIH Human Brain Project Travel Award of $500 Organization for Human Brain Mapping
06/2000 NIH Human Brain Project Travel Award of $500 Organization for Human Brain Mapping
01/1998 Neuroplasticity: Interface of basic and applied Sciences in Clinical Practice Retreat- $350 American Physical Therapy Association, Section on Research
01/1996 Travel award to attend 20th Annual Neural Control of Spatial Behavior Symposium-$350 University of Rochester Center for Visual Science
04/1995 Graduate Student Travel Funds Award-$250 University of Iowa
03/1995 Scholarly Presentation Travel Funds Award-$200 University of Iowa
02/1995 Travel endowment gift of $200 University of Iowa Graduate College Isabel Demple Estate
01/1995 Travel award to attend Multisegmental Motor Control Retreat-$250 American Physical Therapy Association
02/1994 Graduate Student Senate Travel Funds Award-$200 University of Iowa
01/1994 Scholarly Presentation Funds Award-$225 University of Iowa
04/1993 Sims- Riddle Fund Tavel Award-$200 University of Iowa
03/1993 Scholarly Presentation Travel Funds Award–$200 University of Iowa
02/1993 Graduate Student Senate Travel Funds Award-$200 University of Iowa
01/1993 Student Association Research Grant Committee Award-$150 University of Iowa
01/1991 Graduate Student Senate Travel Funds Award-$200 University of Iowa